Use Etoricoxib (the active substance of Monox) is used to relieve symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also used for gouty arthritis and to relieve short-term pain during dental procedures. How to take The medicine is intended for oral administration. Dosage and treatment regimen depend on the disease and doctor's recommendations. Typically, 0.06 to 0.12 g (60 mg to 120 mg) is taken once a day. In case of hepatic insufficiency, it is not recommended to take more than 60 mg of the drug per day. Contraindications The medicine is contraindicated for use: - in case of allergy to the active substance (etoricoxib) or a group of substances; - if the patient has bronchial asthma, recurrent nasal polyposis or sinuses, and intolerance to NSAIDs or aspirin (observed previously); - in case of ulcers and erosions in the stomach and duodenum; - in patients with inflammatory bowel diseases, Crohn's disease, ulcerative colitis, or gastrointestinal bleeding; - in patients with hemophilia, with impaired blood clotting processes; - in case of cerebrovascular or other type of bleeding; - if the patient has severe chronic or acute heart failure (classes 2-4); - in case of serious liver diseases; - in patients with severe renal insufficiency, hyperkalemia, with progressive kidney diseases; - in case of peripheral artery diseases; - in patients with ischemia; - in pregnant women at any stage; - if the patient has recently undergone coronary artery bypass grafting; - with elevated blood pressure, if hypertension reaches more than 140 mmHg by 90 mmHg; - in children under 16 years of age; - during breastfeeding.