Use GUM Trav-Ler 1.1mm x6 (1414) interdental brushes are recommended for use after each meal to prevent food debris accumulation in interdental spaces and bacterial plaque formation on teeth and gums. They can also be used twice a day - in the morning and before bed, before or after regular brushing. How to take - To use, gently insert the brush into the interdental space and perform at least 6 back-and-forth movements. - After each use, rinse the brush under water. - The brush should be replaced as soon as it wears out (usually 7-10 days after the first use). Contraindications - Do not force the brush if the interdental space is too narrow. - Slight bleeding may occur during the first use of the interdental brush, but it should then disappear.