Siofor coated tablets 850mg №60

Use Siofor 850 is indicated for type 2 diabetes mellitus, especially in overweight patients when diet and physical activity are ineffective. It can be used as monotherapy or in combination with other oral hypoglycemic agents and insulin. How to take The standard initial dose is 500 mg once daily or 850 mg once daily. 10-15 days after starting the drug, a further gradual increase in dose is possible, guided by blood glucose levels. A gradual increase in dose helps reduce gastrointestinal side effects. The maximum dose for children is 2000 mg per day, divided into 2-3 doses. The insulin dose is determined based on blood glucose levels. When switching from another oral antidiabetic agent, its use should be discontinued, and metformin hydrochloride should be started at the indicated dose. To improve glycemic control, metformin hydrochloride and insulin can be used in combination, with metformin hydrochloride prescribed at a standard initial dose of 850 mg 2 or 3 times a day, and the insulin dose determined based on blood glucose measurement. Contraindications Siofor 850 is contraindicated during pregnancy and breastfeeding. It is also contraindicated in case of impaired liver and kidney function. It should be used with caution in children and elderly patients. If creatinine clearance is below 30 ml/min, the drug should be immediately discontinued.