Use: Credanil 25/250 is used for Parkinson's disease and parkinsonism, including symptoms such as muscle rigidity, bradykinesia, tremor, and dysphagia. How to take: The drug is taken orally. The initial dose is 1/4 tablet (250 mg/25 mg) 2-3 times a day. Then the dose is gradually increased by 1/4 tablet every 2-3 days until an optimal therapeutic effect is achieved. Usually, the optimal effect is observed when taking 1-2 tablets (250 mg/25 mg each) per day. The maximum daily dose is 1.5 g of levodopa and 150 mg of carbidopa, which corresponds to 6 tablets of 250 mg/25 mg. Contraindications: Credanil 25/250 is contraindicated in: - hypersensitivity to the components of the drug - angle-closure glaucoma - severe psychosis or psychoneurosis - melanoma (including history and suspected cases) - skin diseases of unknown etiology - pregnancy - lactation period - age under 12 years The drug should be used with caution in: - myocardial infarction with rhythm disturbances (history) - bronchial asthma - lung diseases - epileptic seizures (history) - erosive and ulcerative lesions of the gastrointestinal tract - diabetes mellitus and other decompensated endocrine diseases - severe hepatic and/or renal insufficiency - chronic heart failure (CHF) Concurrent use of monoamine oxidase inhibitors is also contraindicated.