Use - Peptic ulcer of the duodenum and stomach in the acute phase. - Prevention of relapse of peptic ulcer of the duodenum and stomach. - Symptomatic ulcers. - Erosive gastroduodenitis. - Gastroesophageal reflux disease (GERD). - Zollinger-Ellison syndrome. - Prevention of aspiration of gastric juice during operations under general anesthesia (Mendelson's syndrome). - Prevention of relapse of bleeding from the upper gastrointestinal tract. How to take - For peptic ulcer of the duodenum and stomach in the acute phase, symptomatic ulcers, erosive gastroduodenitis, GERD: 20 mg twice daily or 40 mg once daily before bedtime. If necessary, the daily dose can be increased to 80-160 mg. The course of treatment is 4-8 weeks. - Prevention of relapse of peptic ulcer: 20 mg once daily before bedtime. - Zollinger-Ellison syndrome: initial dose 20 mg every 6 hours. The dose may be increased depending on the patient's condition. - Prevention of aspiration of gastric juice: 40 mg on the evening before surgery and/or 40 mg on the morning of the operation day. - Prevention of relapse of bleeding from the upper gastrointestinal tract: 20 mg twice daily. - In case of renal insufficiency (creatinine clearance less than 30 ml/min or serum creatinine level more than 3 mg/100 ml): the daily dose should be reduced to 20 mg. Contraindications - Pregnancy. - Lactation period. - Childhood. - Hypersensitivity to famotidine and other components of the drug.