Fromilid coated tab 250mg №14

Use Fromilid is used to treat infectious and inflammatory diseases caused by clarithromycin-sensitive pathogens. These include: - upper respiratory tract and ENT organ infections (tonsillopharyngitis, otitis media, acute sinusitis) - lower respiratory tract infections (acute bronchitis, exacerbation of chronic bronchitis, community-acquired bacterial and atypical pneumonia) - odontogenic infections - skin and soft tissue infections. The drug is also used for mycobacterial infections (M. avium complex, M. kansasii, M. marinum, M. leprae) and their prevention in AIDS patients, as well as for the eradication of Helicobacter pylori in patients with duodenal or gastric ulcers (only as part of combination therapy). How to take Information on the dosage regimen (how to take) was not fully presented in the available snippets. For exact instructions on taking the drug, it is necessary to refer to the full instructions on the source website. Contraindications Contraindications to the use of Fromilid include: - prolonged QT interval on ECG in history, ventricular arrhythmia or torsades de pointes ventricular tachycardia - hypokalemia (due to the risk of QT interval prolongation on ECG) - severe hepatic insufficiency simultaneously with renal insufficiency - cholestatic jaundice/hepatitis in history, developed during clarithromycin use - porphyria - first trimester of pregnancy - breastfeeding period. Concomitant use of clarithromycin is also contraindicated with: - astemizole, cisapride, pimozid, terfenadine - ergot alkaloids (e.g., ergotamine, dihydroergotamine) - oral midazolam - HMG-CoA reductase inhibitors (statins) that are significantly metabolized by CYP3A4 isoenzyme (lovastatin, simvastatin) - colchicine - ticagrelor or ranolazine. Hypersensitivity to clarithromycin and other macrolides is also a contraindication.