Zanidip-Recordati coated tablets 10mg №28

Use Zanidip-Recordati is prescribed for the treatment of essential hypertension (primary arterial hypertension) of mild to moderate severity in adult patients. How to take Zanidip-Recordati is administered orally at 10 mg once daily, at least 15 minutes before a meal, preferably in the morning. Tablets should be swallowed whole with an adequate amount of water. The dose can be increased to 20 mg depending on the achieved antihypertensive effect. The dose increase should be gradual, as it may take about 2 weeks for the maximum antihypertensive effect to manifest. Zanidip-Recordati should not be taken with grapefruit juice. Contraindications - Pregnancy and breastfeeding period. Use in women of childbearing age who are not using reliable methods of contraception. - Children under 18 years of age (efficacy and safety have not been studied). - Severe liver dysfunction. - Severe renal impairment (creatinine clearance less than 30 ml/min), including patients undergoing hemodialysis. - Unstable angina. - Obstruction of the left ventricular outflow tract, including aortic stenosis. - Period after myocardial infarction (up to 1 month). - Concomitant use with cyclosporine. - Concomitant use with potent inhibitors of the CYP3A4 isoenzyme (ketoconazole, itraconazole, ritonavir, erythromycin, troleandomycin). - Concomitant intake with grapefruit or grapefruit juice. - Lactase deficiency, lactose intolerance, glucose-galactose malabsorption.