Allopurinol tablets 100mg №30

Use Allopurinol is used for the treatment and prevention of gout and hyperuricemia of various origins, including conditions associated with nephrolithiasis, renal failure, and urate nephropathy. The drug is also indicated for recurrent mixed oxalate-calcium kidney stones in the presence of hyperuricosuria and increased urate formation due to enzymatic disorders. It is used to lower blood uric acid levels when diet is ineffective. Allopurinol is also prescribed for various hemoblastoses, cytostatic and radiation therapy for tumors, psoriasis, extensive traumatic injuries, Lesch-Nyhan syndrome, as well as during massive glucocorticosteroid therapy when the amount of purines in the blood significantly increases. How to take Allopurinol should be taken orally, once a day after meals, with plenty of water. To reduce the risk of side effects, it is recommended to start with a dose of 100 mg once a day, with subsequent increases if necessary. If the daily dose exceeds 300 mg or symptoms of gastrointestinal intolerance are observed, the dose should be divided into several administrations. Tablets can be divided using a score line. Tablets should not be chewed or crushed. For adults and children over 10 years old, the usual dose is 100-300 mg per day. The maximum single dose is 300 mg, and the maximum daily dose is 800 mg. Contraindications Allopurinol is contraindicated in cases of hypersensitivity to the components of the drug, severe renal dysfunction, and hepatic insufficiency. Contraindications also include excessive iron accumulation in tissues, asymptomatic elevation of urates in the blood, acute gout attack, pregnancy and breastfeeding, as well as children under 3 years of age. Allopurinol should be used with caution in patients with impaired renal function, requiring a dose reduction.