Use: Egiloc is used for arterial hypertension (both as monotherapy and in combination with other hypotensive agents), for the prevention of angina attacks, for heart rhythm disorders (supraventricular tachycardia, extrasystole), for secondary prevention after myocardial infarction, for hyperkinetic cardiac syndrome (including hyperthyroidism, neurocirculatory dystonia), and also for the prevention of migraine attacks. How to take: The average daily oral dose is 100 mg in 1-2 administrations (morning and evening). If necessary, the daily dose can be gradually increased to 200 mg in 2 administrations. In case of renal dysfunction, no dose adjustment is usually required. In liver cirrhosis, no dose adjustment is usually required, however, in severe hepatic insufficiency, a dose reduction may be necessary. In elderly patients, no dose adjustment is required. Contraindications: - Cardiogenic shock. - AV block II and III degree. - Sinoatrial block. - Sick sinus syndrome (SSS). - Severe bradycardia (heart rate less than 50 beats per minute). - Decompensated heart failure. - Angiospastic angina (Prinzmetal's angina). - Severe arterial hypotension (systolic blood pressure below 100 mm Hg). - Lactation period. - Concomitant use of MAO inhibitors. - Concomitant intravenous administration of verapamil. - Hypersensitivity to metoprolol and other components of the drug. - AV block I degree. - Chronic obstructive pulmonary disease (COPD) and mild bronchial asthma. - Diabetes mellitus. - Severe renal insufficiency. Storage: Store at a temperature from 15 to 25 degreeC.