Use Carvedilol is used for arterial hypertension (both as monotherapy and in combination with diuretics), chronic heart failure (as part of combination therapy), and ischemic heart disease (stable angina). How to take The drug is taken orally. The initial dose is usually 12.5 mg once daily, then the dose can be increased to 25 mg once daily. If necessary, the dose can be increased once every two weeks; the maximum dose is 50 mg per day. In elderly patients, a dose of 12.5 mg per day may be effective. (For 6.25 mg tablets, this means that the initial dose of 12.5 mg corresponds to taking two tablets). Contraindications Carvedilol is contraindicated in acute and decompensated chronic heart failure requiring intravenous inotropic agents, severe hepatic insufficiency, AV block II-III degree, pronounced bradycardia (less than 50 beats per minute), sick sinus syndrome (SSS), arterial hypotension (systolic BP less than 85 mm Hg), cardiogenic shock, and chronic obstructive pulmonary disease (COPD). The drug is also contraindicated in children under 18 years of age (efficacy and safety have not been established) and in cases of hypersensitivity to carvedilol or other components of the drug. Carvedilol is contraindicated during pregnancy and lactation (breastfeeding), as well as in liver function disorders.