Use Zoledronic acid is used for the following conditions: - Postmenopausal osteoporosis (to reduce the risk of hip, vertebral, and non-vertebral fractures, to increase bone mineral density). - Prevention of subsequent (new) osteoporotic fractures in men and women with proximal hip fractures. - Osteoporosis in men. - Prevention and treatment of osteoporosis caused by glucocorticosteroid (GCS) use. - Prevention of postmenopausal osteoporosis (in patients with osteopenia). - Paget's disease of bone. How to take The drug is administered by intravenous drip. The dose and treatment regimen are determined depending on the indications and therapeutic efficacy. Contraindications - Hypersensitivity to zoledronic acid or other bisphosphonates. - Severe renal impairment (creatinine clearance less than 35 ml/min). - Pregnancy. - Breastfeeding period. - Children under 18 years of age.