Use Ketilept is used in adults aged 18 years and older for the treatment of the following psychiatric disorders: - Acute and chronic psychoses, including schizophrenia. - Treatment of manic episodes in bipolar disorder. - Treatment of moderate to severe depressive episodes in bipolar disorder. - The drug is not indicated for the prevention of manic and depressive episodes. How to take Ketilept is taken orally, regardless of food intake, 2 times a day. - Adults: The total daily dose for the first 4 days of therapy is 50 mg (Day 1), 100 mg (Day 2), 200 mg (Day 3), and 300 mg (Day 4). Depending on the clinical effect and individual sensitivity, the effective therapeutic dose can range from 150-750 mg/day. - Patients with impaired liver and/or kidney function: The starting dose is 25 mg/day. The daily dose increase should be 25-50 mg until an optimal effect is achieved. - Elderly patients: The recommended starting dose is 25 mg/day, then the dose should be increased by 25-50 mg/day until an effective dose is reached, which is usually lower than in younger patients. Contraindications - Hypersensitivity to any of the components of Ketilept. - Pediatric age (efficacy and safety have not been studied). - Concomitant use with cytochrome P450 3A4 inhibitors, such as HIV protease inhibitors, some azole antifungal agents, antibiotics (erythromycin, clarithromycin), and nefazodone (used for the treatment of depression). Storage Store at a temperature of 2 to 25 degreeC. In a dry place.