Use - Arterial hypertension, including renovascular. - Chronic heart failure (as part of combination therapy). - Left ventricular dysfunction after myocardial infarction in a clinically stable state. - Diabetic nephropathy against the background of type 1 diabetes mellitus (with albuminuria over 30 mg/day). How to take Captopril is taken orally one hour before meals. The dosing regimen is established individually. For arterial hypertension, the initial dose is 12.5 mg (1/2 tablet of 25 mg) twice a day. For mild to moderate arterial hypertension, the usual maintenance dose is 25 mg twice a day, the maximum dose is 50 mg twice a day. For severe arterial hypertension, the initial dose is 12.5 mg twice a day, with a gradual increase to a maximum daily dose of 150 mg (50 mg three times a day). For chronic heart failure, the initial daily dose is 6.25 mg (1/4 tablet of 25 mg) three times a day. The average maintenance dose is 25 mg 2-3 times a day, and the maximum is 150 mg per day. Contraindications Pregnancy, lactation period, age under 18 years, hypersensitivity to captopril and other ACE inhibitors.