Exforge H coated tablets 5mg/160/mg/12.5mg №14

Use: Exforge H is prescribed for the treatment of essential hypertension in adult patients with blood pressure that is adequately controlled by a combination of amlodipine, valsartan, and hydrochlorothiazide. This applies to cases where these components are used as three separate drugs or as two drugs, one of which is a combination. How to take: Exforge H tablets should be taken orally with a small amount of water once daily, regardless of food intake. The recommended daily dose is one tablet. It is advisable to take the tablets in the morning, at the same time. The tablet should be swallowed whole. Dose adjustment is not required for patients with mild to moderate renal impairment. Contraindications: - Hypersensitivity to amlodipine, valsartan, hydrochlorothiazide, other sulfonamide derivatives, dihydropyridine derivatives, or any other excipients of the drug. - Pregnancy and planning for pregnancy. - Lactation period. - Severe renal impairment (creatinine clearance less than 30 ml/min), anuria, and for patients on hemodialysis. - Severe arterial hypotension (systolic blood pressure less than 90 mmHg), collapse, cardiogenic shock. - Severe hepatic impairment (Child-Pugh score > 9), biliary cirrhosis, and cholestasis. - Clinically significant aortic stenosis. - Hypokalemia, hyponatremia, hypercalcemia, and hyperuricemia with clinical manifestations refractory to adequate therapy. - Hereditary angioedema or edema developed during previous therapy with angiotensin II receptor antagonists. - Age under 18 years, as efficacy and safety have not been established. - Systemic hyperuricemia, as the drug contains hydrochlorothiazide.