Lorista H coated tablets 100mg/12.5mg №28

Use Lorista H is indicated for the treatment of arterial hypertension in patients for whom combination therapy is indicated. It is also used to reduce the risk of cardiovascular morbidity and mortality in patients with arterial hypertension and left ventricular hypertrophy, which is manifested by a cumulative reduction in the frequency of cardiovascular mortality, stroke, and myocardial infarction. How to take The drug is taken orally, regardless of food intake, with a sufficient amount of water, once a day. Lorista H can be used simultaneously with other antihypertensive drugs. The combination of hydrochlorothiazide/losartan is indicated for patients in whom separate use of hydrochlorothiazide or losartan does not provide adequate blood pressure control. Dose titration of losartan and hydrochlorothiazide is recommended before transferring the patient to Lorista H therapy. Contraindications Lorista H has the following contraindications: - Hypersensitivity to any of the components of the drug. - Anuria. - Severe renal impairment (creatinine clearance less than 30 ml/min). - Severe hepatic impairment. - Concomitant use with aliskiren in patients with diabetes mellitus or renal impairment (creatinine clearance less than 60 ml/min). - Age under 18 years (efficacy and safety have not been established). - Hypokalemia or hypercalcemia resistant to therapy. - Refractory hyponatremia. - Symptomatic hyperuricemia/gout. - Lactase deficiency, lactose intolerance, glucose-galactose malabsorption syndrome, as Lorista H contains lactose. - Pregnancy. - Breastfeeding period. Storage Store at a temperature not exceeding 25 degreeC, in the original packaging (blister). Keep out of reach of children.