Co-Sentor tablets 50mg/12.5mg №30

Use Ko-Sentor film-coated tablets are indicated for the treatment of arterial hypertension in patients whose blood pressure is not adequately controlled with monotherapy of losartan or hydrochlorothiazide. How to take Ko-Sentor should be taken orally, regardless of food intake, with a glass of water. The drug can be used as part of combination therapy with other antihypertensive agents. The combined preparation of losartan and hydrochlorothiazide is not intended for use as initial therapy. Ko-Sentor is prescribed for the treatment of patients with insufficient hypotensive effect when taking only losartan or only hydrochlorothiazide. The most common maintenance dose of Ko-Sentor is one Ko-Sentor 50 mg/12.5 mg tablet once daily. The antihypertensive effect is usually achieved within three to four weeks after the start of therapy. Contraindications - Hypersensitivity to active substances, sulfonamide derivatives, or any excipient of the drug. - Uncorrectable hypokalemia or hypercalcemia. - Severe hepatic insufficiency, cholestasis, or biliary obstruction. - Refractory hyponatremia. - Severe renal insufficiency (creatinine clearance <30 ml/min), anuria. - Pregnancy and breastfeeding period. - Concomitant use with aliskiren in patients with diabetes mellitus or renal impairment. - Children and adolescents under 18 years of age (no experience of use).