Ko-Vamloset tablets 10mg/160mg/12.5mg №30

Use Ko-Vamloset is indicated for use in adults with arterial hypertension of II and III degrees. How to take Ko-Vamloset should be taken orally with a small amount of water, regardless of mealtime. The recommended daily dose is 1 tablet, containing amlodipine + valsartan + hydrochlorothiazide in a dose of 10 mg + 160 mg + 12.5 mg. Ko-Vamloset is taken once a day. The dose of Ko-Vamloset is selected after prior titration of doses of monocomponent medicinal products containing the active substances included in Ko-Vamloset. Contraindications - Hypersensitivity to amlodipine, valsartan, hydrochlorothiazide, other sulfonamide and dihydropyridine derivatives, as well as other excipients of the drug. - Hereditary angioedema, or edema in patients on prior therapy with angiotensin II receptor antagonists (ARBs). - Pregnancy, planning pregnancy, and breastfeeding period. - Hepatic insufficiency, biliary cirrhosis, and cholestasis. - Severe renal impairment (creatinine clearance < 30 ml/min), anuria, patients on hemodialysis. - Hypokalemia, hyponatremia, hypercalcemia refractory to adequate therapy, as well as hyperuricemia with clinical manifestations. - Age under 18 years. - Severe arterial hypotension (systolic BP < 90 mm Hg), collapse, cardiogenic shock. - Clinically significant aortic stenosis. - Hemodynamically unstable heart failure after acute myocardial infarction. - Concomitant use with aliskiren and ACE inhibitors. Storage At a temperature not higher than 25 degreeC, in the original blister packaging. Keep out of reach of children.